Indeed, our previous study confirmed that the levels of cellular glutathione (GSH) in human bone marrow-derived MSCs depended on culture conditions [8]
Secondly, HOCl/OH can activate enzyme complexes involved in DNA repair (such as APE1, PARP, DNA ligase) to assemble at DNA damage sites, promoting chromatin decondensation and further enhancing NETs/NETosis [247]
Studies suggest its potential to promote neural growth factors, which could have implications for neuroprotection and neurodegenerative models relevant to diseases such as Alzheimers in preclinical settings
The adoption of large-scale collaborative research, standardization of definitions and analyses, pilot examination of interventions, and improvement in study design standards, peer review, reporting, and dissemination of research have been identified as crucial actions to enhance the validity of scientific works (302)