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This can happen due to various reasons, including excessive sweating, vomiting, diarrhea, or not drinking enough fluids

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Front Aging Neurosci 9:365 Dodge JC, Haidet AM, Yang W, Passini MA, Hester M, Clarke J, Roskelley EM, Treleaven CM, Rizo L, Martin H, Kim SH (2008) Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity

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