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Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome

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We then performed qPCR analysis on genes related to the aspartateglutamate pathway ( Mdh1 , Mdh1b , Mdh2 , Got1 and Got2 ), beta-cell communication and insulin secretion ( Epha5 and Efna5 ) and senescence ( Grem1 and Cd38 )

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