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This has been reported to have resulted in a 7% absolute increase in the number of patients admitted to hospital for paracetamol poisoning [2]
The effectiveness of the inhibitor, combined with the lack of toxicity, makes inhibition of aspartate aminotransferase a potentially successful chemotherapeutic target
368 Astrocytes exposed to excessive ammonium start to generate aberrant Ca 2+ signals, which may cause excitotoxic release of glutamate
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