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Malodor in smokers is the result of nicotine in tobacco products, which increases the blood supply and reduces the coral pink color of the gums

You have a pre-existing medical condition, such as an autoimmune disorder or liver disease

Moreover, negative media coverage or reports of adverse events can lead to increased scrutiny from regulatory bodies and public hesitation, hindering acceptance in the mainstream healthcare setting

For example, proteins such as histone 1, H2A, H4, and leucine-rich repeat protein are overexpressed in antimony-resistant parasites, while proteins like the kinetoplastid membrane protein (KMP-11) are under-expressed (Das et al., 2015)