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Trafficking to the cell surface of amino acid transporter SLC6A14 upregulated in cancer is controlled by phosphorylation of SEC24C protein by AKT kinase
What they did: They took 80 rats (Wistar strain), completely transected their Achilles tendon (the strongest tendon in the body) and divided them into 3 groups: Control , saline BPC-157 by injection , 10 g/kg into the abdominal cavity BPC-157 in drinking water , 10 g/kg orally After 14 days they tested the tensile strength of the healed tendon and performed histology (microscopic examination of the tissue)
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Quercetin , the rutin-lysine-generated MRP, effectively inhibits free radicals, enhances activity of antioxidant enzymes (i.e., SOD and CAT), initiates Nrf2-dependent pathway, and upregulates phase II detoxifying antioxidant genes (including NQO1, HO-1, GCLG, and GCLM) 621
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