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Most unabsorbed LC has been described to be broken down by digestive tract microbes [1]

The aforementioned studies suggest that SSRIs may contribute to the development of fetal myocardial injury, while also affecting maternal calcium homeostasis and steroid metabolism as well as inducing endocrine dysfunction, intrauterine fetal growth restriction, and neonatal maladaptation to the extrauterine environment (Figure 2)

Here are a few reasons for this: Proteolysis (protein digestion): Protein digestion is likely to be impaired in hypothyroidism, but tends to be accelerated in hyperthyroidism

In their research, Fangfang et al