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The most commonly reported adjustment period is a few days of temporary digestive change -- mild gas or altered bowel habits -- when starting a new probiotic product

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The department said its review ensures that differences between these products do not affect the safety, efficacy, or quality of the drug, and that Health Canada will continue to monitor authorized generic semaglutide products and take action if unexpected safety or effectiveness concerns arise [Source: canada.ca/en/health-canada/news/2026/05/canada-approves-second-generic-semaglutide-the-first-g7-country-to-do-so.html]

GLP-1 receptor agonists and gastrointestinal motility: Clinical review