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however, there is reasonable agreement that with aging comes the increased likelihood of compromised innate immunity, oxidative stress-induced damage, infection and neuroinflammation accompanied by microgliosis [2,3,39-42]

[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Neschen S, Morino K, Hammond LE, Zhang D, Liu ZX, Romanelli AJ, et al

A common acronym used by medical professionals and the lay public to identify the suspicious features of pigmented lesions that may reflect malignant change is ABCDE :[5] A symmetry of the lesion

P., & Sloop, K