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Atkuri, J

The sample was prepared as follows: samples (20 l) were quenched with 200 l 4:1 methanol:water in Eppendorf tubes, vortexed, and centrifuged for 2 min at 21,300 g

Oral GLP-1 formulations are adding manufacturing complexity in a different dimension: on December 22, 2025, the FDA approved Novo Nordisk's oral Wegovy 25 mg as the first oral GLP-1 therapy for weight loss, bringing with it the manufacturing requirements of oral solid dosage pharmaceutical production at commercial scale, a fundamentally different infrastructure challenge from parenteral peptide API synthesis

We use molecular modeling to predict how ingredients interact, and digital twins to scale up with precision, says Albe