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This may explain the comparatively high discontinuation rate of 10.6% for those on the highest dose of orforglipron, a higher figure than the 7% observed for the investigational oral semaglutide

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[DOI] [PMC free article] [PubMed] [Google Scholar] 226.Lagaye S, Shen H, Saunier B, Nascimbeni M, Gaston J, Bourdoncle P, Hannoun L, Massault PP, Vallet-Pichard A, Mallet V, et al