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NSAIDs primarily reduce inflammation by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the production of prostaglandins, which are involved in the inflammatory response, including the promotion of pain, fever, and tissue damage

The small molecule nobiletin targets the molecular oscillator to enhance circadian rhythms and protect against metabolic syndrome

Health care professionals should review CMS eligibility criteria, covered products, prior authorization requirements, and patient support resources to help identify patients who may qualify

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