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Vitamin C acts as a cofactor for the enzymes prolyl hydroxylase and lysyl hydroxylase, which are required for collagen formation
It accelerates wound closure, reduces scarring, and promotes the formation of new blood vessels (angiogenesis) a critical component of tissue repair
Coronavirus infection and PARP expression dysregulate the NAD metabolome: an actionable component of innate immunity
6 The screening model is valuable precisely because it is sensitive, but that sensitivity is also its limitation: many agents that look promising on dermal papilla cells never translate into clinically meaningful regrowth, because a follicle in a dish is insulated from the hormonal, vascular, immune, and mechanical realities of a living scalp
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