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These results potentially demonstrate a role of GLP-1 in preferentially acting on the liver and inducing hepatic glucose disposal and glycogenesis over that of skeletal muscle, given that endogenous GLP-1 is normally secreted in response to nutrient absorption following a fed state

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Statins remain the gold-standard first-line treatment for elevated LDL cholesterol, capable of reducing LDL levels by 3050% depending on dose and agent