glutathione metabolism and its implications for health system enhancement cardiac protection: pharmacological options against oxidative stress ferroptosis REGULATION OF GLUTATHIONE SYNTHESIS -

When the "safe" pathways in the liver become overwhelmed, more of the medication is pushed through the pathway that creates NAPQI

Poor diet, lack of sleep, overworking the mind and body, heavy metal exposure, medications, pesticides, strong household and personal care products can wreak havoc on organs, blood vessels and cells in general causing such problems as premature aging, reduced function, slowing or lowering energy, stiffening joints and causing memory to decline among other issues

(PubMed) Kucukgoncu S, Zhou E, Lucas KB, Tek C

It is not known whether taking glutathione during pregnancy is safe or poses any risks