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The initial signs and symptoms often include a lesion that is soft to palpation, usually pigmented, initially asymptomatic, with irregular borders and a color spectrum ranging from dark brown to bluish-black, occasionally presenting variations of gray, purple, and red due to ulcerations, or depigmentation (Figure 5) [39,40]

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Ensembl), and exonic unique molecular identifier (UMI) counts were used for downstream analysis

Many people see noticeable results in around 4 weeks