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[245] [247] Because of its behavior as a prodrug and its pharmacokinetic differences, lisdexamfetamine has a longer duration of therapeutic effect than immediate-release dextroamphetamine and shows reduced misuse potential

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Mitochondrial glutathione is particularly critical for protecting against oxidative damage, as mitochondria lack the enzymes for glutathione synthesis and must import it from the cytosol via specific transport systems

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