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When testing their ability to conjugate ubiquitin to NHR-49 in vitro, WWP-1 successfully transferred ubiquitin, resulting in detectable polyubiquitinated species, whereas HECD-1 failed to do so (Fig

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You should first make an appointment to see your GP who will perform a skin check, examine any lesions or moles of concern and if needed, refer you to a skin specialist / dermatologist for professional clinical assessment