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Intrahepatic triglyceride, intramuscular fat, liver glycogen, muscle glycogen, extracellular fluid DXA reads all of these as some combination of "lean" and "fat" mass without separating them

It is a vicious cycle: You take the injectable drug Your appetite is low You eat less calories Your energy is low (because you eat less calories) You dont exercise (because your energy is low) Your body breaks down muscle to create energy The scale shows you have lost weight, but it is from loss of muscle Weight loss is important if you are overweight, but losing muscle is counterproductive

Fink et al., 2022

62 Existing problems in these studies There are several limitations that should be considered when interpreting these results