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TNF-alpha induced shedding of the endothelial glycocalyx is prevented by hydrocortisone and antithrombin

It is released in pulses, mostly at night during deep sleep, with the largest pulse typically occurring in the first 60 to 90 minutes after sleep onset

PMCID: PMC7108996

Diagnosis of OSA requires the following: (i) the presence of nocturnal breathing disturbances and respiratory disturbance index or apnoea-hypopnoea index (AHI) (the average amount of apnoea plus hypopnoea events/sleep hour (h)) 5