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It has been shown that free radicals ( Reference Ambrosio, Flaherty and Duilio 50 , Reference Bolli, Zughaib and Li 51 ) and inflammatory cytokines ( Reference Kukielka, Smith and Manning 52 ) have a key role in reperfusion injury process

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This can generally be managed by combining propofol with a low-dose vasopressor infusion (e.g., phenylephrine or norepinephrine) to counteract the vasodilation caused by propofol