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It describes them as most appropriate for patients who cannot tolerate GLP-1 medications, those with a GLP-1 contraindication such as personal or family history of medullary thyroid carcinoma, or people whose situation calls for a different metabolic pathway

Some stress markers of FF and serum, including malondialdehyde (MDA), 8-Oxo-2-deoxyguanosine (8-OHdG), and thiol oxidation, are associated with lower embryo quality, whereas higher Total Antioxidant Capacity (TAC) correlates with better fertilization rates and higher pregnancy success [75,76,77,78]

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2012, 2012: 569654- Chalmers J, MacMahon S, Patel A, Cooper M, Ferrannini E, Glasziou P, Grobbee D, Hamet P, Harrap S, Heller S: Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes