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Dispense a few drops of the serum onto your fingertips and gently massage it into your face and neck, avoiding the eye area

Key Takeaways Loose skin is a structural issue: Significant weight loss stretches the physical matrix of the skin, which no cream can shrink back down

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The number of self-reported current somatic diseases (including cardiometabolic, respiratory, musculoskeletal, digestive, neurological, endocrine diseases and cancer) for which participants received medical treatment was counted (coded as 0, 1, 2+) as a global marker of poor physical health