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Originally investigated as a potential treatment for Alzheimers disease, Dihexa demonstrates potent ability to enhance synaptic connections and promote neuronal survival through modulation of hepatocyte growth factor (HGF) and its receptor c-Met, which play crucial roles in brain development and neuronal health

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In contrast, a GSSR intermediate was detected and its decreased steady-state concentration at higher glutaredoxin concentrations was suggested to support monothiol mechanism (i) 60