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Reported side effects are generally mild and may include localized pain or redness at the injection site

The freezing process can drive freeze-concentration, where the acid and peptide separate into pockets that concentrate the acid and can damage the peptide structure during thawing

Dose-response studies show therapeutic effects from 10 g/kg to 10 mg/kg in rats with no reported adverse events, suggesting a broad therapeutic window that would extrapolate to 50250 mg in humans