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That said, estrogen has well-documented effects on insulin sensitivity, fat distribution, and metabolic risk, which makes it reasonable to ask whether hormone status modifies response to anti-obesity pharmacotherapy

The elimination of coverage for anti-obesity medication follows a broader trend among major state providers and insurers, including the Group Insurance Commission (GIC) and Blue Cross Blue Shield of Massachusetts, with officials citing unsustainably high prescription costs

The gustatory signaling pathway and bitter taste receptors affect the development of oobesity and adipocyte metabolism in mice

Eur J Pharmacol (2018) 823:110