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Description

Upon switching to monthly dosing, a mild, transient increase in nausea and/or vomiting was observed, but these symptoms improved rapidly with continued dosing

However, some contraindications to GH therapy are present in subjects with PWS, such as severe obesity or severe respiratory impairment, acute critical illness, uncontrolled diabetes, active cancer, and active psychosis (118)

BED subjects have substantial decrements in their ventral striatal reward pathways and diminished ability to recruit fronto-cortical impulse-control circuits to implement dietary restraint

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