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We previously showed that oral intake of long-term oscillating glucose (LOsG, 4 times/day for 38 days) can lead to -cells gaining metabolic memory in reactive oxygen species (ROS) stress, inhibition of insulin and SOD-2 expression, and the development of prediabetes with hypoinsulinemia and glucose intolerance [3]

Understanding these qualification standards helps patients determine whether they might be appropriate candidates for this treatment approach

Patients frequently report improved sleep quality as nighttime hunger fades, along with better hormonal regulation overall especially in individuals with insulin resistance or metabolic dysfunction

J Clin Endocrinol Metab 100(11):40374047