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The final predicted expression of both CBS OPT and L2HGDH OPT were MYPYDVPDYALQISCBS OPT (or L2HGDH OPT )DYKDDDDKKSRGPGRATGAAANSAVDGTAGPGSTGSRVDGSGEGRGSLLTCGDVEENPGP (with the features: HA tag, amino acid linker 1, CBS OPT (or L2HGDH OPT ), FLAG, amino acid linker 2, T2A self-cleavage site, in the order of N to C terminal) (#230088 and #230089, Addgene)

Platelet-derived microparticles (PMPs) have been demonstrated to play a role in the increased incidence of atherosclerotic plaque and arterial thrombosis formation in individuals (182, 183)

In addition, of eight antibodies that were effective agonists for the GHR/G-CSFR hybrid, only one antibody acted as an agonist with weak activity on full-length GHR, suggesting that receptor dimerization alone is not sufficient for activation (46)

The use of stomach acid-resistant capsules (DRcaps) further protects glutathiones stability