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This phenomenon is due to the upregulation of the expression of glutamine transporters or enzymes by oncogenes such as c-MYC, which accelerate the uptake and metabolism rate of glutamine and then drive the TCA and biosynthetic processes [3, 16] (Fig

This effect is likely to be mediated through several pathways: a) Upregulation of antioxidant enzymes: The significant increase in catalase levels observed in the IF group suggests that IF enhances endogenous antioxidant defenses, as catalase is a key enzyme in detoxifying hydrogen peroxide and mitigating oxidative stress

Those reactions are more concerning if they worsen, spread, become hot, drain fluid, or come with fever or systemic symptoms

The research conducted thus far is foundational, aiming to deepen our understanding of GHK-Cus therapeutic potential through rigorous scientific inquiry, without venturing into direct applications