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We conducted a comprehensive literature search across databases, including PubMed and Web of Science, compiling data from clinical trials, case reports, and basic research studies published up to 2025, with a focus on the efficacy, safety, and mechanism of action of drugs such as liraglutide, semaglutide, and tirzepatide in patients with MC4R deficiency

3, 2025, pp

It does not build muscle, improve your relationship with food, or teach you how to eat when you come off it

Qualitative and mixed-methods research has demonstrated that patients perspectives provide valuable insights into medication effects, shifting expectations, experiences of stigma, and evolving identity [83,84,85]