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The peptide was first isolated during experiments in rabbits and named for its reported association with increased electroencephalographic delta activity

Taking your unique needs and situation into account, your doctor or nurse practitioner will recommend a dosage that will treat your condition with the fewest possible side effects

An animal study conducted by Koeth and colleagues found that TMAO decreases the bile acid pool size and inhibits the expressions of the key BA synthetic enzymes (Cyp7a1 and Cyp27a1) and BA transporters (Oatp1, Oatp4, Mrp2, and Ntcp) in the liver (Koeth et al., 2013)