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In the phase 2 trial, the 1 mg dose group showed minimal weight change at early time points

In a clinical trial specifically designed for weight loss, participants using Semaglutide GLP-1 experienced an average loss of up to 15% of their initial body weight over a 68-week period

Another trial, this one of exenatide, showed no significant changes in amyloid or tau in participants cerebrospinal fluid (the clear liquid around the brain) but it did find a reduction in amyloidbeta in extracellular vesiclespackages cells release to communicate with each otherwhich could be an early biomarker of Alzheimers disease, per the researchers

Ezekowitz, M