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doi: 10.1186/s13148-020-00837-1 296 GilbertWVBellTASchaeningC

PMID: 10199753 Houston J.B

In addition, the possible causes of brain iron metabolism disorder may include cell mitochondrial and lysosomal dysfunction

Mitochondrial morphology and function were analyzed by confocal microscopy and oxygen consumption rate, respectively, while mitochondrial membrane potential, intracellular reactive oxygen species (ROS) levels and GSH/GSSG ratio were evaluated by fluorescence-based assays