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Table 1 Comparisons of ratios of product to precursor in purine pathway

Taking Ozempic and Zepbound during the same week is dangerous and dramatically increases the risk of severe dehydration, profound hypoglycemia, and gastrointestinal complications

The decreased melatonin levels may, in part, be explained by increased levels of interleukin-6, a pro-inflammatory cytokine, which induces monoamine oxidase A, which leads to an increase in the breakdown of serotonin, a precursor of melatonin 138,139

Beyond glucose metrics, GLP-1 therapy offers cardiovascular protectiona benefit particularly important for people with prediabetes, who carry elevated heart disease risk