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Analysts even recently trimmed some forecasts on sales to reflect increased pressure thanks to the GLP-1 updates

Some advanced protocols include morning or post-workout doses , especially when stacked with other GH secretagogues like MK677

However, this outcome fell short of the anticipated 25% weight reduction, potentially limiting its competitive edge against Eli Lillys ZEPBOUND, which reported up to 20.9% weight loss in the SURMOUNT-1 trial. In the subsequent REDEFINE 2 trial, which focused on adults with obesity or overweight and type 2 diabetes, CagriSema achieved a 15.7% mean weight loss after 68 weeks, compared to 3.1% with placebo

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