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doi: 10.1016/j.cell.2015.07.017

When projects span months, traceability becomes a central part of defensible science because it allows investigators to connect outcomes to specific material references and preparation assumptions

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These data collectively demonstrate that: (i) doxorubicin is the principal cytotoxic driver, (ii) liposomal encapsulation enhances both DOX and BC bioactivity through improved uptake and controlled release, (iii) co-encapsulation preserves DOX potency (equivalent MTT IC) while amplifying downstream mechanistic endpoints, and (iv) the superior anticancer efficacy of BCDOX-Lipo arises from synergistic reinforcement of the G/S checkpoint coupled with sustained apoptotic commitment