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Miller PR, Narayan RJ, Polsky R

Furthermore, research leaders and developers emphasize that combination therapy may offer the greatest potential for treating such a multifaceted disorder

It is also the appropriate choice for study designs where researchers want to isolate the contribution of GIPR agonism to metabolic outcomes with semaglutide as the GLP-1R mono-agonist control and tirzepatide as the dual-agonist comparator