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241 A phase 1/2 (ECHO-202/KEYNOTE-037) trial evaluating the effectiveness of the IDO1 inhibitor epacadostat combined with pembrolizumab on advanced solid tumors showed a high objective response rate (ORR) of 40.3% overall and 61.9% in malignant melanoma patients, demonstrating promising antitumor efficacy

In contrast with the CON group, hepatopancreas GSH content was lower in group HL, although there was no statistically significant difference, which may be attributed to the increased production of ROS induced by high-lipid diets depleting the antioxidant GSH (Qu et al., 2022)

This is called a contingency fee agreement

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