While retatrutide microdosing has not been formally studied for GI mitigation specifically, the principle is sound based on the dose-response data from clinical trials

Sofwave is ideal for treating mild to moderate skin laxity in areas such as: Face: Sagging cheeks, jowls, and fine lines Neck: Loose skin and horizontal tech lines Arms: Crepey texture and mild sagging Abdomen: Postpartum or age-related laxity Multiple ultrasound beams technology provides high levels of coverage with each pulse Proven clinical efficacy Simple, intuitive, and fast treatment improves practice patient workflow EXCEPTIONAL Safety Profile Integrated epidermis cooling Sofcool Real-time skin temperature monitoring Treats all skin types No damage to the underlying structures HIGH Patient Satisfaction Non-invasive, no interruption to daily routine Fast treatment: ~30 to 45 minutes Consistent results Sofwaveis an FDA cleared, non-invasive treatment of fine lines and wrinkles using a next generation SUPERB Synchronous Ultrasound Parallel Beam Technology

At 80 weeks, all doses of retatrutide (4 mg, 9 mg, and 12 mg) met the primary and key secondary endpoints for obesity, delivering clinically meaningful weight loss
Available from: Fletcher MM, Halls ML, Christopoulos A, Sexton PM, Wootten D (2016) The complexity of signalling mediated by the glucagon-like peptide-1 receptor