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Even small amounts of food, beverages other than water, or other medications can interfere with absorption

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Summary: GLP-1 receptor agonists commonly cause acid reflux and heartburn by delaying gastric emptying, which increases stomach pressure and promotes reflux of stomach contents into the oesophagus

This Fc domain serves a dual function: it sterically hinders access to DPP-4, thereby protecting the GLP-1 moiety from enzymatic degradation, and it engages the neonatal Fc receptor (FcRn), facilitating receptor-mediated recycling and preventing lysosomal degradation following cellular uptake