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Dosing and How to Take Them Semaglutide Dosing For weight loss (Wegovy): Start: 0.25 mg weekly for 4 weeks Increase gradually to 2.4 mg weekly Take as injection under the skin once per week Also available as daily pill (Rybelsus) for diabetes Tirzepatide Dosing For weight loss (Zepbound): Start: 2.5 mg weekly for 4 weeks Can increase up to 15 mg weekly Take as injection under the skin once per week Only available as injection, not as pills Both medications work best when you increase the dose slowly

High-intensity interval training works well for time-efficient options, though appetite effects sometimes favor steady-state cardio during peak side effect weeks

Still, sustainable metabolic health ultimately requires thinking beyond a single hormone, Missimer says

HR leaders can help employees manage out-of-pocket expenses by showing how HSAs cover prescriptions like GLP-1s