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Analysis based on BRAF mutation status revealed a more pronounced therapeutic advantage of mRNA-4157 combined with pembrolizumab in BRAF-mutant patients (HR 0.332) relative to wild-type patients (HR 0.808)
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The unmodified cysteine residue for the ATR-107 peptide is also predicted to reside at P3 and be TCR-facing when bound by HLA-DRB1*07:01
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