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For instance, both brain-specific or whole-body SIRT1-overexpressing transgenic mice exhibit a slowed aging and a prolonged lifespan

Its structure and stability make it a frequent subject of study in controlled experimental settings

Finally, in a small nonrandomized, unblinded, controlled study in 42 obese children (mean age, 8 years) with MAFLD, lifestyle recommendations combined with 600 mg/day of supplemental RRR --tocopheryl acetate for six months reduced markers of oxidative stress and liver dysfunction and improved insulin sensitivity and the profile of lipid in the blood, when compared to baseline