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The STEP trials for semaglutide 2.4 mg in weight management showed mean weight loss of 14.9% from baseline at 68 weeks

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in: PubMed | Google Scholar | Published July 14, 2020 - More info Postprandial triglycerides (TGs) are elevated in people with type 2 diabetes (T2D)

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In fact, insulin therapy can sometimes lead to weight gain, as it helps store excess calories in the form of fat

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By modulating macrophage polarization towards an M2 subtype, GLP-1RAs can inhibit inflammation occurring in the vessel lumen, an action which would alleviate the progression of atherosclerosis (Figure 2)

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