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The ecto-enzymes CD39 and CD73, expressed on Tregs, catalyze the metabolism of ATP (Adenosine triphosphate) into AMP (Adenosine monophosphate) and in turn, produce the immunoregulatory purine, adenosine ( in vivo ( 3) Induction of apoptosis

Protoplasma 65 , 223238 (1968)

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