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The evidence is weak, because the required concentration of the thrombospondin-1 peptide exceeded the thrombospondin-1 concentration in plasma by 10 3 10 4 (Lutz, 2013) and the phenomena had been studied on RBC that (a) were not actively leucocyte-depleted and (b) were oxidatively damaged by CuSO 4 and ascorbic acid rather than in vivo aged

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Glutathione performs countless essential jobs, including: Neutralizing free radicals Supporting liver detoxification pathways Protecting mitochondria Recycling other antioxidants Supporting immune function Helping remove environmental toxins The body's ability to handle ongoing toxic exposures declines when glutathione stores become depleted