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Furthermore, several novel GLS inhibitors have exhibited superior therapeutic efficacy in clinical settings and preliminary studies, such as IN-3, have been shown to possess antiproliferative effects on PCa

72 NAC NAC is a cysteine prodrug and hepatic GSH precursor, and should be administered immediately as an antidote in patients with established APAP hepatotoxicity or those with high risk of developing this condition

Patients in the phase 3b clinical trial maintained about 75-80% of their weight loss and health benefits, such as reduced waist circumference and improvements in blood pressure, blood sugar, triglycerides and cholesterol levels