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4 13 The gastric effect, by contrast, is a matter of autonomic output: descending signals adjust vagal tone to the stomach, changing the mechanical rate at which it empties

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elegantly demonstrated that neural stem cell secretomes inhibit microglial activation via BDNF/VEGF signaling, but their work neglected gastrointestinal dysbiosis, overlooking the bidirectional crosstalk now recognized as central to ASD pathophysiology [42]

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