A follow-up review by Coury and colleagues, published in Pediatrics in 2012, called for a research agenda specifically focused on gastrointestinal conditions in autism, citing the consistency and severity of the problem [2]
Cohorts receiving VK2735 also demonstrated reductions in mean body weight relative to placebo, ranging up to 3.3%
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In the intention-to-treat (ITT) analysis, cohort members were followed from index date until first registration of suicide or suicide attempts, emigration, death, switching to the other study drug or end of follow-up (31 December 2022)